RSV Resources for DOs

RSV on the rise

Stay updated on the latest developments in prevention of RSV

Explore resources focused on RSV symptoms, management and prevention.

Last updated: October 2023

The following resources have been curated by the AOA division of health programs development to help physicians stay updated on the latest RSV treatment and prevention protocols.

Helpful links

Osteopathic.org:

Centers for Disease Control and Prevention:

National Institutes of Health (NIH)

Clinical Trials: RSV

National Institute of Allergy and Infectious Disease

Respiratory Syncytial Virus (RSV) Vaccine Approval for People 60 years+

Food and Drug Administration

FDA Approves First Respiratory Syncytial Virus (RSV) Vaccine

Articles & research

View research studies and systematic reviews on RSV prevention and symptom management.

Pediatric Population

Garegnani L, Styrmisdóttir L, Roson Rodriguez P, Escobar Liquitay CM, Esteban I, Franco JV. Palivizumab for preventing severe respiratory syncytial virus (RSV) infection in children. Cochrane Database Syst Rev. 2021 Nov 16;11(11):CD013757. doi: 10.1002/14651858.CD013757.pub2. PMID: 34783356; PMCID: PMC8594174.
Sanders SL, Agwan S, Hassan M, van Driel ML, Del Mar CB. Immunoglobulin treatment for hospitalized infants and young children with respiratory syncytial virus infection. Cochrane Database Syst Rev. 2019 Aug 26;8(8):CD009417. doi: 10.1002/14651858.CD009417.pub2. PMID: 31446622; PMCID: PMC6708604.
Andabaka T, Nickerson JW, Rojas-Reyes MX, Rueda JD, Bacic Vrca V, Barsic B. Monoclonal antibody for reducing the risk of respiratory syncytial virus infection in children. Cochrane Database Syst Rev. 2013 Apr 30;(4):CD006602. doi: 10.1002/14651858.CD006602.pub4. PMID: 23633336.
Liu F, Ouyang J, Sharma AN, Liu S, Yang B, Xiong W, Xu R. Leukotriene inhibitors for bronchiolitis in infants and young children. Cochrane Database Syst Rev. 2015 Mar 16;(3):CD010636. doi: 10.1002/14651858.CD010636.pub2. PMID: 25773054.
Farley R, Spurling GK, Eriksson L, Del Mar CB. Antibiotics for bronchiolitis in children under two years of age. Cochrane Database Syst Rev. 2014 Oct 9;(10):CD005189. doi: 10.1002/14651858.CD005189.pub4. PMID: 25300167.
Liet JM, Ducruet T, Gupta V, Cambonie G. Heliox inhalation therapy for bronchiolitis in infants. Cochrane Database Syst Rev. 2015 Sep 18;2015(9):CD006915. doi: 10.1002/14651858.CD006915.pub3. PMID: 26384333; PMCID: PMC8504435.
Roqué i Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C, Vilaró J. Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old. Cochrane Database Syst Rev. 2016 Feb 1;2(2):CD004873. doi: 10.1002/14651858.CD004873.pub5. PMID: 26833493; PMCID: PMC6458017.
Enriquez A, Chu IW, Mellis C, Lin WY. Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months. Cochrane Database Syst Rev. 2012 Nov 14;11(11):CD008395. doi: 10.1002/14651858.CD008395.pub2. PMID: 23152257; PMCID: PMC7388903.

Adult population

Walsh E, Lee N, Sander I, Stolper R, Zakar J, Mahadevia J, Wyffels V, Myers D, Fleishhackl R. Burden of respiratory syncytial virus (RSV) disease in adults: final analysis from a retrospective chart review. European Respiratory Journal. 2017 Sep, 50 (suppl 61) PA3314: DOI: 10.1183/1393003.congress2017.PA3314.
Weinberg A, Lambert SL, Canniff J, Yu L, Lang N, Esser MT, Falloon J, Levin MJ. Antibody and B cell responses to an investigational adjuvanted RSV vaccine for older adults. Hum Vaccin Immunother. 2019;15(10):2466-2474. doi: 10.1080/21645515.2019.1589282. Epub 2019 Jun 3. PMID: 30852939; PMCID: PMC6816353.
Cicconi P, Jones C, Sarkar E, Silva-Reyes L, Klenerman P, de Lara C, Hutchings C, Moris P, Janssens M, Fissette LA, Picciolato M, Leach A, Gonzalez-Lopez A, Dieussaert I, Snape MD. First-in-Human Randomized Study toAssess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults. Clin Infect Dis. 2020 May 6;70(10):2073-2081. doi: 10.1093/cid/ciz653. PMID: 31340042; PMCID: PMC7201425.
Hansen CL, Chaves SS, Demont C, Viboud C. Mortality Associated With Influenza and Respiratory Syncytial Virus in the US, 1999-2018. JAMA Netw Open. 2022 Feb 1;5(2):e220527. doi: 10.1001/jamanetworkopen.2022.0527. PMID: 35226079; PMCID: PMC8886548.
Midgley CM, Haynes AK, Baumgardner JL, Chommanard C, Demas SW, Prill MM, Abedi GR, Curns AT, Watson JT, Gerber SI. Determining the Seasonality of Respiratory Syncytial Virus in the United States: The Impact of Increased Molecular Testing. J Infect Dis. 2017 Aug 1;216(3):345-355. doi: 10.1093/infdis/jix275. PMID: 28859428; PMCID: PMC5712458.
Branche AR, Saiman L, Walsh EE, Falsey AR, Jia H, Barrett A, Alba L, Phillips M, Finelli L. Change in functional status associated with respiratory syncytial virus infection in hospitalized older adults. Influenza Other Respir Viruses. 2022 Nov;16(6):1151-1160. doi: 10.1111/irv.13043. Epub 2022 Sep 7. PMID: 36069297; PMCID: PMC9530534.
McLaughlin JM, Khan F, Schmitt HJ, Agosti Y, Jodar L, Simões EAF, Swerdlow DL. Respiratory Syncytial Virus-Associated Hospitalization Rates among US Infants: A Systematic Review and Meta-Analysis. J Infect Dis. 2022 Mar 15;225(6):1100-1111. doi: 10.1093/infdis/jiaa752. PMID: 33346360; PMCID: PMC8921994.